Comparison of ultrasound and maceration methods on antioxidant and antimicrobial efficacy of phenolic compounds extracted from <i>Cynodon dactylon</i> L. of Algeria

Abstract An investigation was carried out to extract the polyphenols from Cynodon dactylon L. by ultrasound-assisted extraction (UAE) and maceration assisted (MAE), assess antioxidant antimicrobial activities, as well evaluation of cytotoxic effect ethanolic extracts. The yields crude extracts were 9.40 % for MAE 12.52 UAE extract. results showed that obtained contains a high level flavonoids estimated 42.14 ± 0.75 mg EAG/gE 23.57 0.78 EQ/gE. In contrast, content condensed tannins in (19.34 0.48 EC/gE) is higher. activity revealed considerable response, represents most active extract, with an IC 50 =7.52 0.037 mg/mL DPPH test, 15.83 0.37 EAA/gE FRAP test. all strains targeted have susceptibility two cytotoxicity against RBCs carried, shown non-toxic C. hence support its ethnomedicinal application.